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Steroid 11-beta-Hydroxylase
CYP11B1 | Cytochrome P-450 CYP11B1 | Cytochrome P-450(11 beta) | Steroid 11-beta-Monooxygenase | 11 beta-Hydroxylase | CYP 11B1 | Cytochrome P450 11B1 | Steroid 11 Hydroxylase | Steroid 11-Hydroxylase | Steroid-11-Hydroxylase | 11 beta Hydroxylase
A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11B1 gene, is important in the synthesis of CORTICOSTERONE and HYDROCORTISONE. Defects in CYP11B1 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL). |
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